益生菌在毛滴虫感染防治中的作用以及应用前景
程怡秋
(
广东广垦畜牧集团股份有限公司
, 广东 , 广州 510610
)
江家豪
(
广东省农业科学动物卫生研究所
, 广东 , 广州 510640
)
罗霜
(
广东省农业科学动物卫生研究所;华南农业大学兽医学院
, 广东 , 广州 510640
)
蔡海明
(
广东省农业科学动物卫生研究所
, 广东 , 广州 510640
)
李结
(
广东广垦畜牧集团股份有限公司
, 广东 , 广州 510610
)
中图分类号:S855.9
文献标志码:A
文章编号:1008-3847(2025)12-0002-07
作者简介:程怡秋,硕士,水产动物营养,主要从事畜牧相关研究,35369393@qq.com。
# 同等贡献作者:江家豪,硕士,预防兽医学,lwjhero123@126.com。
* 通讯作者:蔡海明,博士,生物化学与分子生物学,caihaiming@gdaas.cn;
李结,硕士,高级兽医师,预防兽医学,13822287099@163.
com。
摘要:
毛滴虫感染是一种常见的寄生虫病,严重危害人类与动物健康。目前,硝基咪唑类药物是治疗该病的首选,
但其副作用与耐药性问题日益突出,亟需开发新的防治策略。益生菌以其安全性高、作用机制多样等特点受到广泛关注,
渐成为防治毛滴虫病的一个有前景的替代。本文综述了毛滴虫感染与宿主微生物群落变化的关系,系统总结了益生菌
在预防和治疗毛滴虫感染中的潜在作用机制,并对其安全性及未来发展前景进行了探讨。研究表明,益生菌可通过调
节宿主微生物群落、增强黏膜屏障功能、调节免疫反应等多种途径抑制毛滴虫感染。尽管益生菌展现出良好的应用前景,
但其具体作用机制和临床效果仍需进一步验证。未来应着重开发针对性强、安全性高的益生菌制剂,并探索其与传统
疗法联合使用的可能性,为毛滴虫病的防控提供新思路。
关键字:
毛滴虫病 微生物群落 益生菌 替代疗法
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